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Mounjaro Vs Wegovy: What’s the Difference? – Day Lewis

Mounjaro Vs Wegovy: What’s the Difference?

Mounjaro® and Wegovy® are both leading injectable treatments for weight loss, that are administered weekly. Although both drugs work in similar ways, they are not the same.

The active ingredient in Mounjaro® is called Tirzepatide. This ingredient activates two hormonal receptors GIP and GLP-1. When activated, these receptors work to suppress the appetite, regulate blood sugar levels and slow the rate of food leaving the stomach – all of which results in weight loss.

The active ingredient in Wegovy® is called Semaglutide. This works by mimicking the hormonal receptor GLP-1, resulting in the same actions mentioned above. The only difference, Wegovy® does not mimic GIP.

Can you switch from Mounjaro to Wegovy?

Switching weight loss treatments is possible but should always be guided by your local Day Lewis pharmacist.

You must not take Mounjaro and Wegovy together as this can cause some serious side effects.

Dosages:

Mounjaro has 6 doses, with a starting dose of 2.5mg, which you’ll take for 4 weeks. The other Mounjaro doses are:

  • 5mg
  • 7.5mg
  • 10mg
  • 12.5mg
  • 15mg

The maintenance doses for Mounjaro are: 5mg, 10mg, or 15mg. You can stay on a lower maintenance dose if you’re happy with your results or get side effects at a higher dose.

Wegovy has 5 doses, with a starting dose of 0.25mg, which you’ll also take for 4 weeks. The other Wegovy doses are:

  • 0.5mg
  • 1mg
  • 1.7mg
  • 2.4mg – the maintenance dose

Is Wegovy or Mounjaro more effective?

Wegovy and Mounjaro have both been shown in clinical studies to effectively support weight loss.

In one trial, patients taking Wegovy (Semaglutide) experienced up to a 16.9% reduction in body weight after 68 weeks of treatment.

For Mounjaro (Tirzepatide), another trial found weight reductions of up to 22.5% after 72 weeks.

It’s important to note that for best results, treatment should be combined with healthy lifestyle habits, including a balanced diet and regular physical activity including resistance training.

Individual responses can vary, and patients may experience different side effects or outcomes with either medication. For more information speak to your local Day Lewis Pharmacist today.

Which is more cost effective?

Eli Lilly, the manufactures of Mounjaro, recently announced a price increase for all strengths of their weight loss treatment. This has left many patients already taking Mounjaro concerned about its affordability, making Wegovy a more affordable treatment option that also provides results.

To support our existing patients on Mounjaro, Day Lewis will be absorbing up to 50% of the price increase.

Always consult with your healthcare provider to ensure treatment methods are suitable for you.

Side effects of Mounjaro & Wegovy?

Very common side effects:

Mounjaro Wegovy
  • nausea (feeling sick)
  • diarrhoea
  • vomiting (being sick)
  • constipation
  • stomach pain
  • headache
  • nausea
  • vomiting
  • diarrhoea
  • constipation
  • stomach pain
  • feeling weak or tired

Common side effects:

Mounjaro Wegovy
  • allergic reaction, including itching, rash, or eczema
  • dizziness
  • stomach pain
  • low blood pressure
  • indigestion
  • bloating
  • burping
  • gas
  • reflux
  • heartburn
  • hair loss
  • tiredness or fatigue
  • injection site reactions
  • an increased level of lipase (a pancreatic enzyme) in the bloodstream
  • low blood sugar (when used for the treatment of type 2 diabetes alongside both metformin and a sodium-glucose co-transporter 2 inhibitor)
  • increased levels of calcitonin in the bloodstream (a hormone regulating calcium levels in your blood)
  • gallstones
  • indigestion
  • dizziness
  • upset stomach
  • hair loss
  • burping
  • gas
  • bloating
  • inflamed stomach
  • heartburn or reflux
  • gallstones
  • injection site reactions
  • low blood sugar in diabetic patients

Uncommon side effects:

Mounjaro Wegovy
  • an increased level of amylase (a pancreatic enzyme) in the bloodstream
  • pain at the injection site
  • cholecystitis (infection of the gallbladder)
  • fast pulse
  • low blood sugar (in type 2 diabetes treatment when taken with metformin)
  • change in skin sensation
  • change in sense of taste
  • a delay in the emptying of the stomach
  • a delay in the emptying of the stomach
  • fast heartbeat
  • an increase in pancreatic enzymes in the bloodstream

 

For more information, click here to book now for a FREE consultation.

 

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Picture of Author: Rachna Chhatralia MRPharmS

Author: Rachna Chhatralia MRPharmS

Superintendent Pharmacist
GPHC number: 2045909

Rachna brings over 25 years of experience to her role as Superintendent. She qualified as a pharmacist at the London School of Pharmacy and has been working for Day Lewis since 2002. Her career is distinguished by a commitment to excellence in patient care, a deep understanding of pharmacy operations and a proactive approach to healthcare management.

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